1 | // This file is a part of Framsticks GenoFX library.
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2 | // Copyright (C) 2002-2009 Maciej Komosinski. See LICENSE.txt for details.
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3 | // Refer to http://www.framsticks.com/ for further information.
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4 |
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5 | #include "geno_ftest.h"
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6 | #include "nonstd.h" //randomN, rnd01
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7 |
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8 | /** \file
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9 | Sample output (simple examples of various genetic operations):
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10 | \anchor geno_ftest_example
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11 | \include geno_ftest_example
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12 | Produced by the source:
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13 | \include geno_ftest.cpp
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14 | */
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15 |
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16 | #define FIELDSTRUCT Geno_ftest
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17 | static ParamEntry GENOtestparam_tab[]= //external access to ftest genetic parameters
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18 | {
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19 | {"Genetics: ftest",1,1,},
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20 | {"ftest_mut",0,0,"Mutation probability","f 0 1",FIELD(prob),"How many genes should be mutated during single mutation (1=all genes, 0.1=ten percent)",},
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21 | {0,},
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22 | };
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23 | #undef FIELDSTRUCT
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24 |
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25 | Geno_ftest::Geno_ftest()
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26 | {
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27 | par.setParamTab(GENOtestparam_tab);
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28 | par.select(this);
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29 | supported_format='t'; //'0' for f0, '1' for f1, etc.
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30 | prob=0.1;
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31 | }
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32 |
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33 | ///The only letters allowed are A,T,G,C
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34 | int Geno_ftest::checkValidity(const char* gene)
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35 | {
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36 | if (!gene[0]) return 1; //empty is not valid
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37 | bool ok=true;
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38 | int i;
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39 | for(i=0;i<strlen(gene);i++) if (!strchr("ATGC",gene[i])) {ok=false; break;}
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40 | return ok ? GENOPER_OK : i+1;
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41 | }
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42 |
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43 | ///Remove all invalid letters from the genotype
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44 | int Geno_ftest::validate(char *&gene)
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45 | {
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46 | SString validated; //new genotype (everything except ATGC is skipped)
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47 | for(int i=0;i<strlen(gene);i++)
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48 | if (strchr("ATGC",gene[i])) validated+=gene[i]; //validated contains only ATGC
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49 | free(gene);
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50 | gene=strdup(validated); //reallocate
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51 | return GENOPER_OK;
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52 | }
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53 |
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54 | ///Very simple mutation
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55 | int Geno_ftest::mutate(char *&gene,float &chg)
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56 | {
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57 | static char a[]="ATGC";
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58 | int changes=0,len=strlen(gene);
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59 | for(int i=0;i<len;i++)
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60 | if (rnd01<prob) //normalize prob with length of genotype
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61 | {gene[i]=a[randomN(4)]; changes++;}
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62 | chg=(float)changes/len;
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63 | return GENOPER_OK;
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64 | }
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65 |
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66 | ///A simple one-point crossover
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67 | int Geno_ftest::crossOver(char *&g1,char *&g2,float& chg1,float& chg2)
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68 | {
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69 | int len1=strlen(g1),len2=strlen(g2);
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70 | int p1=randomN(len1); //random cut point for first genotype
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71 | int p2=randomN(len2); //random cut point for second genotype
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72 | char *child1=(char*)malloc(p1+len2-p2+1);
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73 | char *child2=(char*)malloc(p2+len1-p1+1);
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74 | strncpy(child1,g1,p1); strcpy(child1+p1,g2+p2);
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75 | strncpy(child2,g2,p2); strcpy(child2+p2,g1+p1);
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76 | free(g1); g1=child1;
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77 | free(g2); g2=child2;
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78 | chg1=(float)p1/strlen(child1);
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79 | chg2=(float)p2/strlen(child2);
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80 | return GENOPER_OK;
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81 | }
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82 |
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83 | ///Applying some colors and font styles...
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84 | unsigned long Geno_ftest::style(const char *g, int pos)
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85 | {
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86 | char ch=g[pos];
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87 | unsigned long style=GENSTYLE_CS(0,GENSTYLE_INVALID); //default, should be changed below
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88 | if (ch=='A') style=GENSTYLE_RGBS(200,0,0,GENSTYLE_BOLD);
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89 | if (ch=='T') style=GENSTYLE_RGBS(0,200,0,GENSTYLE_BOLD);
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90 | if (ch=='G') style=GENSTYLE_RGBS(0,0,200,GENSTYLE_NONE);
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91 | if (ch=='C') style=GENSTYLE_RGBS(200,200,0,GENSTYLE_NONE);
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92 | return style;
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93 | }
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94 |
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95 |
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96 | #ifdef GENO_FTEST_APPL //define this macro to compile a simple testing main function
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97 |
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98 | Geno_ftest gft;
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99 |
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100 | void main()
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101 | {
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102 | float chg;
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103 | char *g=strdup(gft.getSimplest());
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104 | for(int i=0;i<10;i++)
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105 | {
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106 | int result=gft.mutate(g,chg);
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107 | printf("%s [mutated %.1f%%]\n",g,chg*100);
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108 | }
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109 |
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110 | char *g2=strdup(gft.getSimplest());
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111 | float chg2;
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112 | printf("\nCrossing over the last mutant, \n\t%s\nand the simplest genotype\n\t%s\n:\n",g,g2);
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113 | gft.crossOver(g,g2,chg,chg2);
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114 | printf("Offspring 1:\n\t%s (%.1f%% genes from parent1)\n",g,chg*100);
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115 | printf("Offspring 2:\n\t%s (%.1f%% genes from parent2)\n",g2,chg2*100);
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116 | free(g);
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117 | free(g2);
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118 |
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119 | g=strdup("ATGsomethingCG");
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120 | printf("\nChecking genotype:\n\t%s... error at position %d.\n",g,gft.checkValidity(g));
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121 | gft.validate(g);
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122 | printf("After validation:\n\t%s\n",g);
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123 | free(g);
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124 | printf("...and is YOUR genotype O.K.?\n\n");
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125 | }
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126 |
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127 | #endif
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128 |
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